Get to Know the Symptoms and Causes of Depression

The Holistic Bio Spa is excited to have Jake Ames, MD, HMD  back to share his expertise on depression.


This is a very complicated subject to write about. It is necessary to always try to find the cause of your depression instead of taking a drug to treat your symptoms of depression.

What is Depression?

Depression is a mood disorder and may have some of these symptoms:

  • Sadness
  • Lethargy
  • Inactivity
  • Difficulty in thinking
  • Deficits in memory and concentration
  • Feelings of hopelessness and despair
  • Feelings of dejection
  • Suicidal tendencies

Causes and symptoms of depression

I divide the causes and symptoms of depression into different categories. Many of these categories overlap.

  1. Biochemically induced
  2. Induced by pharmaceuticals
  3. Hormone imbalance (deficiency or excess)
  4. Lack of Sunshine
  5. Amino acid deficiency or imbalance (lack of neurotransmitters)
  6. Heavy metal, toxins and chemical poisonings
  7. Emotionally based
  8. Genetic (MTHFR mutation)
  9. Electromagnetic fields and “dirty electricity”
  10. Lack of exercise
  11. Lack or orgasms
  12. Lack of purpose and life goals
  13. Lack of essential fatty acids (omega 3’s & omega 6’s)
  14. Lack of cellular oxygen
  15. Lack of rest and sleep
  16. Lack of self-love and respect
  17. Lack of parental love
  18. Lack of education and self-esteem
  19. Lack of job fulfillment and salary
  20. Poor physical and emotional health
  21. Lack of hobbies
  22. Lack of giving to family, friends, and humanity
  23. Too many nanoparticles in the brain and body.
  24. Lack of cell-membrane phosphatidylcholine

You can see this is an extensive list, and your first visit with your physician should be at least for one-hour. Your physician should do comprehensive laboratory blood tests and hair analysis. I prefer to use Doctors Data Company in Chicago, Illinois for the hair analysis. I have done thousands of hair analysis from them, and I consider Doctors Data to be one of the best hair analysis labs in the world. The hair analysis is a screening test for heavy metals, and it correlates quite well with red blood cell (RBC) mineral testing.

Your blood tests should include the MTHFR mutation, CBC, full chemistry panel including the fasting lipid panel, liver panel, GGT, ionized calcium, total T4, Total T3, Free T3, TSH, thyroid autoantibodies, urinalysis, fibrinogen, CRP-HS, homocysteine, and lipoprotein (a). Your physician should be an expert in interpreting these laboratory tests since optimal ranges are different than the laboratory’s reference range.

You need to have ALL of your mercury amalgam dental fillings and root canals removed. Your dentist should check to see if there is no mercury underneath a crown. Try to find a biological dentist who is an expert in removing mercury amalgam fillings, and giving you biocompatible composite fillings if you need them.

You need to have an acupressure treatment with Intention, and see an experienced health kinesiologist. Most of your trauma is stored in your fascia (connective tissue), in your limbic system and amygdala in your brain. Your mind is holographic and fractal, so your physical and emotional traumas are stored in your DNA (epigenetic memories), your fascia (connective tissues), and everywhere in your body and mind, and that includes your electromagnetic field (aura). If you don’t have access to an experienced health kinesiologist, try to find a physician who does electrodermal screening (EDS or EAV). He will hook you up to a biofeedback machine to measure thousands of electrical readings on you. My favorite machine is the SCIO Machine, which we have at the Holistic Bio Spa. The SCIO was invented by Dr. William Nelson, a top NASA scientist who now resides in Hungary.

All of us have heavy metals and nutritional deficiencies. One-hundred percent of us are deficient in more than one essential mineral. Replacing all of these mineral deficiencies is important. Of top importance is to take lithium orotate 5 mg 1-4 at bedtime, working up to 20 mg over a couple of weeks. This is different lithium than what bipolar patients take (see my lithium blog). This lithium will actually help you grow new brain cells, and protect the brain cells that you already have from toxins. It is an essential mineral for mood stabilization. Another important mineral for your brain is boron (see my boron blog).

All of us have mercury in our brains and bodies. Taking supplemental selenium in the form of methylselenocysteine 200 mcg. to 600 mcg a day helps to make mercury, arsenic, and cadmium inert. Your physician should help you decide on your correct daily dose.


Have a biological dentist remove ALL of your root canals and

mercury amalgam dental fillings.


Serotonin is a neurotransmitter which helps depression. The common drugs used to treat depression keep serotonin around longer; they don’t make serotonin. Serotonin is made from the amino acid l-tryptophan, which converts to 5-HTP, then to serotonin. Most of my patients are given 5-HTP as a trial, usually starting at 50-100 mg at bedtime. Too much 5-HTP can cause nightmares and delayed ejaculation.

I put most of my depressed patients on methyl folic acid 10 mg to 15 mg a day (the calcium salt only, not the glucosamine salt).
If you have the MTHFR mutation, you will need to be on methyl folic acid your entire life. Physicians can only test for two of these mutations, whereas there are over 60 of these mutations. Basically, all multivitamins should contain methyl folic acid instead of folic acid.

Hemp seed oil at one tablespoon a day is better balanced with the omega 6 to omega 3 ratio than cod liver oil, krill oil, salmon oil, and flaxseed oil. The ideal omega 6 to omega 3 ratio is 4:1.

I use other supplements and herbs to treat depression, but I don’t have the space to talk about this today.

This is a very comprehensive program for treating depression, and your general health. Every one of us is not functioning fully mentally and physically. We all need nutritional supplementation and to have a balanced lifestyle.


No part of this blog may be reproduced in any form without written permission. The content on this blog is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of qualified health providers with questions you may have regarding medical conditions.

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